Si Andy, Si Lauren, O Si Peng is a story about three cousins who grew up with their uncle, Papang He- the youngest of the Magbanua siblings. Their fathers are seamen and they have lived in different countries and some of them already have families there. Coby will come into their lives, the guy that will test their masculinity and gender identity, will seduce, spread and bring conflicts to each other because his main goal is...revenge. With Coby on vacation at the rest house are his two friends, Angel and BJ, collectively known as ABC Boys. Andy, Lauren and Peng will compete with one another to win Coby's love until eventually only one will be victorious. Coby will find out who took advantage of him but in the end, love will still prevail. It's a story about family, acceptance, second chances and love- that love is love in any form.

Who is the real Magbanua? Who is really the protagonist? Who is the villain? Who will be loved? And who can't be chosen? Andy, Lauren, or Peng?