Mary Knows Best is a docu-soap reality series following Mary Occhino, a successful radio host, psychic intuitive and mother of three, who gives a whole new meaning to the term "mother is always right". Her children, Jacqueline, Chris and Carl are a mismatched group of siblings consisting of a reluctant psychic, a paranormal investigator and a skeptic. In each episode viewers will meet a humorous and unforgettable cast of family characters including Mary's outspoken older brother Charles and two adorable grandchildren.