After years of perfecting their passion for interior design in their own homes, Tish and Brandi Cyrus take their talents to the streets of their hometown, Nashville, to share their skills with friends and word-of-mouth clients. Each 30-minute episode begins as mother and daughter present competing ideas within a given budget for rooms that are in design distress. Once the client chooses a renovation plan, they must work together to turn that vision into a reality on Cyrus vs. Cyrus: Design and Conquer. With décor dilemmas and makeover malfunctions along the way, will this dream team deliver the desired results or crack under pressure?