Mina is about a two twins who grew up in different worlds completely unaware of each other. One is Park Mina, a famous singer, who has arguments with her manager Joon Suh about her secret relationship with the rich Tae Hoon. The other one is Kim Soo Ryun, a poor girl who struggles to make a living. The story takes its fateful turn when Mina is seriously injured in car accident and her manager wants Soo Ryun to take Mina's place. Things get complicated when Soo Ryun slowly falls for Tae Hoon and when a different looking Mina returns to Korea after having plastic surgery.