Cash Cab is a game show that aired on ITV in the United Kingdom from 13 June 2005 to 2006. The original programme that launched the worldwide Cash Cab franchise, it was hosted by John Moody. The questions were asked in voice over style by Annabel Raftery.

The show's host initially poses as an ordinary taxi driver and drives around the major cities of the United Kingdom in a cab. The show pays its passengers for correctly answering standard general knowledge questions. Contestants are recruited in advance but are not told that the quiz will be taking place in the cab, so although the "pick-ups" are not as random as they appear on screen, the contestants are genuinely surprised when the taxi turns out to be the Cash Cab. (This differs from some editions, most notably the Canadian and American versions, wherein the contestants are generally chosen at random and are usually asked on camera if they wish to play or not once the rules are explained to them).

The host of Cash Cab, John Moody, is a genuine qualified taxi driver.