A well-educated bon vivant becomes one of the pioneers of drug trafficking in the eighties. Ignacio "Nacho" Montero starts smuggling cigarettes and transitions to selling marijuana. He joins the most powerful cartel leader of the time, Pablo Escobar, and floods the United States with cocaine. Thanks to dirty business, he meets Isabel - the love of his life - and his inseparable friend, Lieberman. Excesses, violence and illegality will put everything he builds at risk.