When her restaurateur husband, Marco Giannopolous, is found dead under a side of lamb and dripping in gourmet olive oil, Bedfordview housewife and Mrs South Africa entrant, Despina, vows to keep the family businesses going  but then learns the real family business is crime.

Set in the lavish but seedy Johannesburg East suburb, Bedfordview, Bedford Wives follows the lives of four women, and a community of Bedfordview criminals who; on the surface, exude pristine and perfect lives, but behind closed doors, are revealed to have skeletons and secrets.