The series is set in the 21st century, where the existence of humanoid animals that have been living in the darkness for centuries have been revealed to the world. One day, Michiru, who was a normal highschool student, suddenly turns into a tanuki person; running away, she seeks refuge in Anima City, a place set up for humanoid animals to be able to live as themselves. While there, Michiru encounters a wolf person, Shirou Ogami, who goes on to investigate why she became a humanoid animal, and in the process gets mixed up in even stranger events.