How well do you know your family? Do you know each other well enough that, if given the opportunity, your family could win a houseful of flat-screen TVs, kitchen appliances, concert tickets, a car or even receive scholarship money for your children's education? In what could be considered the return of family game night, those dream-of-a-lifetime prizes and more could turn into reality when opportunity comes knocking on the doors of some lucky families on the new one-hour game show, Opportunity Knocks, In Opportunity Knocks, host and executive producer JD Roth will knock on a family's front door in "Anywhere, America," giving them the opportunity to have a family game night where they can win hundreds of thousands of dollars and amazing prizes that could change their lives. Each week the mobile Opportunity Knocks team literally sets up shop on a family's front lawn, where an audience made up of neighbors and friends will be cheering them on.