She Made Me Do It profiles true stories of women accused of manipulating men to do their evil bidding. Although the crimes differ in nature, they all share a common theme – a woman is credited to being the chief mastermind behind-the-scenes. Through witness testimonies, expert interviews and dramatic reenactments, each episode explores criminal cases surrounding the femme fatale. From a romantic reconciliation dinner that ends in homicide to a star athlete who is discovered lifeless with mysterious wounds, viewers will follow the investigation of the alleged perpetrators who claim "She Made Me Do It," hear both sides of the story and ultimately discover the jury's verdict.