The Adventures of Pow Wow featured the pre-adolescent Native-American boy Pow Wow, as well as the tribe's medicine man, and a Native-American girl who was a friend of Pow Wow's. The cartoons often centered on Pow Wow's discovery of an animal, hurt or otherwise, and his attempts to protect the forest and wildlife from various threats. When Pow Wow needed help in these missions, he would seek counsel from the wise medicine man.