Under the rule of a tyrannical empire, Tatsumi, a young swordsman, leaves his home to save his poverty stricken village. He meets a girl named Akame, an assassin who was bought, brainwashed and trained to kill by the Empire. Akame is a member of the secret assassin group called "Night Raid" who use special weapons called Teigu. Together, Tatsumi and the members of Night Raid confront the corrupt empire.